Course Contents
[b]Content[/b]
Introduction into the methods for the lab-scale und preparation of fluoroorganic compounds. The focus will also be on the unique property profile of fluorochemicals, and how that can be utilized for the design of functional materials, industrial chemicals and pharmaceuticals: 
• Properties of fluoroorganic compounds 
• Environmental impact of fluoroorganic chemistry 
• Survey of synthetic methods and reactivity 
• Fluoroorganic materials: the chemistry of liquid crystals 
• Fluoropharmaceuticals and diagnostics: structure-property relationships 
• Fluorous synthesis and catalysis 

 

Literature
1. P. Kirsch. Modern Fluoroorganic Chemistry: Synthesis, Reactivity, Applications (2nd ed). Wiley-VCH, Weinheim (2013) (doi: 10.1002/9783527651351) 
2. A. Haupt. Organic and Inorganic Fluorine Chemistry: Methods and Applications. De Gruyter, Berlin (2021) (doi: 10.1515/9783110659337) 
3. J. Han, A. M. Remete, L. S. Dobson, L. Kiss, K. Izawa, H. Moriwaki, V. A. Soloshonok, D. O’Hagan. Next generation organofluorine containing blockbuster drugs. J. Fluorine Chem. 239, 109639 (2020) (doi: 10.1016/j.jfluchem.2020.109639) 
4. Y. Ogawa, E. Tokunaga, O. Kobayashi, K. Hirai, N. Shibata. Current contributions of organofluorine compounds to the agrochemical industry. iScience (2020) (doi: 10.1016/j.isci.2020.101467) 

Online Offerings
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Semester: Verão 2023