Course Contents
[b]Content[/b]
Introduction into the methods for the lab-scale und preparation of fluoroorganic compounds. The focus will also be on the unique property profile of fluorochemicals, and how that can be utilized for the design of functional materials, industrial chemicals and pharmaceuticals:
Properties of fluoroorganic compounds
Environmental impact of fluoroorganic chemistry
Survey of synthetic methods and reactivity
Fluoroorganic materials: the chemistry of liquid crystals
Fluoropharmaceuticals and diagnostics: structure-property relationships
Fluorous synthesis and catalysis
Literature
1. P. Kirsch. Modern Fluoroorganic Chemistry: Synthesis, Reactivity, Applications (2nd ed). Wiley-VCH, Weinheim (2013) (doi: 10.1002/9783527651351)
2. A. Haupt. Organic and Inorganic Fluorine Chemistry: Methods and Applications. De Gruyter, Berlin (2021) (doi: 10.1515/9783110659337)
3. J. Han, A. M. Remete, L. S. Dobson, L. Kiss, K. Izawa, H. Moriwaki, V. A. Soloshonok, D. OHagan. Next generation organofluorine containing blockbuster drugs. J. Fluorine Chem. 239, 109639 (2020) (doi: 10.1016/j.jfluchem.2020.109639)
4. Y. Ogawa, E. Tokunaga, O. Kobayashi, K. Hirai, N. Shibata. Current contributions of organofluorine compounds to the agrochemical industry. iScience (2020) (doi: 10.1016/j.isci.2020.101467)
Online Offerings
moodle
[b]Content[/b]
Introduction into the methods for the lab-scale und preparation of fluoroorganic compounds. The focus will also be on the unique property profile of fluorochemicals, and how that can be utilized for the design of functional materials, industrial chemicals and pharmaceuticals:
Properties of fluoroorganic compounds
Environmental impact of fluoroorganic chemistry
Survey of synthetic methods and reactivity
Fluoroorganic materials: the chemistry of liquid crystals
Fluoropharmaceuticals and diagnostics: structure-property relationships
Fluorous synthesis and catalysis
Literature
1. P. Kirsch. Modern Fluoroorganic Chemistry: Synthesis, Reactivity, Applications (2nd ed). Wiley-VCH, Weinheim (2013) (doi: 10.1002/9783527651351)
2. A. Haupt. Organic and Inorganic Fluorine Chemistry: Methods and Applications. De Gruyter, Berlin (2021) (doi: 10.1515/9783110659337)
3. J. Han, A. M. Remete, L. S. Dobson, L. Kiss, K. Izawa, H. Moriwaki, V. A. Soloshonok, D. OHagan. Next generation organofluorine containing blockbuster drugs. J. Fluorine Chem. 239, 109639 (2020) (doi: 10.1016/j.jfluchem.2020.109639)
4. Y. Ogawa, E. Tokunaga, O. Kobayashi, K. Hirai, N. Shibata. Current contributions of organofluorine compounds to the agrochemical industry. iScience (2020) (doi: 10.1016/j.isci.2020.101467)
Online Offerings
moodle
- Lehrende: KirschPeer
Semester: ST 2023