Course Contents
The lecture Chemical Biology / Biological Chemistry deals with chemical tools and methods for the investigation of biological questions.
1. Molecular diversity
- Chemical genetics
- Combinatorial chemistry
- Diversity-oriented synthesis
2. Cell-based screening
- Yeast-based screens
- Screens with mammalian cells
- High throughput and high content screening
3. In vitro screening
- Heterogeneous assays and immobilization
- Homogeneous binding assays and labeling
4. Tools based on biomolecules
- Enzyme-based methods
- Nucleic acid-based methods
- Aptamers
- Chemical inducers of dimerization and PROTACs
Official Course Description
The lecture Chemical Biology / Biological Chemistry deals with chemical tools and methods for the investigation of biological questions.
1. molecular diversity
- Chemical genetics
- Combinatorial chemistry
- Diversity-oriented synthesis
2. cell-based screening
- Yeast-based screens
- Screens with mammalian cells
- High throughput and high content screening
3. in vitro screening
- Heterogeneous assays and immobilization
- Homogeneous binding assays and labeling
4. tools from biomolecules
- Enzyme-based methods
- Nucleic acid-based methods
- Aptamers
- Chemical inducers of dimerization and PROTACs
- Lehrende: Katja Schmitz