Course information

Course Contents
The lecture Chemical Biology / Biological Chemistry deals with chemical tools and methods for the investigation of biological questions.

1. In vitro assays for binding and activit
 - Heterogeneous assays and immobilization
 - Homogeneous binding assays and labeling
2. Cell-based screening
 - Yeast-based screens  
 - Screens with mammalian cells
 - High throughput and high content screening  

3. Molecular diversity
 - Chemical genetics
 - Combinatorial chemistry
 - Diversity-oriented synthesis

4. Tools based on biomolecules
 - Enzyme-based methods
 - Nucleic acid-based methods
 - Aptamers
 - Chemical inducers of dimerization and PROTACs