Course Contents
- history of biomedical devices, recent developments, and current challenges
- Regulations/guidelines/standards for biomedical products and processes, German Medical Devices Law, EU legal framework for medical products, biocompatibility and biodegradability of materials, natural and synthetic materials, reaction of tissue to e.g. implants, criteria for the selection of materials
- Stage-gate process for biomedical products
- Function and composition of blood, rheology and mechanical properties of blood as a basis for the calculation and design of medical devices, damage mechanisms of blood and their minimization in the design of medical devices, transport mechanisms of blood, e.g. exosomes
- Fluid dynamics in biological systems, Bernoulli's law, flow in branched channels (e.g., arteries), influence of wall elasticity on flow behavior, oscillatory flow
- Introduction to membrane processes in biomedicine, synthetic and natural membranes, transport resistances, materials and structures, mass transport in membranes, application examples, e.g. dialysis
- Extracorporeal blood treatment, blood purification and separation by membranes
- Mass transport in biological systems, diffusion and sorption, simple binding, e.g. ligand/receptor and complex binding, e.g. extracellular matrix, mass transport within the cell
- Drug transport, drug development, kinetics of drug release, pharmacokinetics, diffusion-controlled membrane systems, transdermal drug release
- Materials, cultivation systems for tissue engineering
Online Offerings
moodle
- Lecturer: John Linkhorst